Fig. 2
From: Peak calling by Sparse Enrichment Analysis for CUT&RUN chromatin profiling
SEACR minimizes true negative detection from a gold standard dataset. a Schematic of SEACR threshold selection. A target/total signal block curve (right) is calculated, and the stringent and relaxed thresholds are set based on the knee and the peak of the curve. b Peaks were called from Sox2 or FoxA2 experiments carried out in either hESCs or Endoderm cells using SEACR in stringent or relaxed mode; MACS2; or HOMER